The Duke Molecular Genetic Pathology (MGP) Fellowship combines advanced clinical training in a high volume, high complexity molecular diagnostics laboratory with myriad opportunities to further academic interests. Training occurs primarily on the main campus of Duke University Hospital in the combined Molecular Pathology, Genetics and Genomics (MPGG) clinical laboratory that processes nearly 17,000 samples for cytogenetic and molecular testing annually. Fellows are exposed to a wide variety of constitutional and oncologic testing using over 50 assays including:

  • Comprehensive genomic profiling (solid tumor)
  • NGS and Sanger sequencing (hematologic malignancy, solid tumor, and constitutional)
  • RNA-based fusion panels (hematologic malignancy, solid tumor)
  • Clonality studies by NGS (T-cell, B-cell, IGH somatic hypermutation)
  • Microarray analysis (constitutional and solid tumor)
  • Methylation assays (PWS/AS, MLH1 promoter)
  • Carrier screening (cystic fibrosis, hemochromatosis, SMA, Fragile X, etc.)
  • qPCR (BCR/ABL1 quantification, somatic mutation detection)
  • STR analysis (bone marrow engraftment, MSI, sample identity, molar pregnancy)
  • Cytogenetics assays including karyotyping and FISH (hematologic malignancy, solid tumor, constitutional)

Program Overview

  • Positions offered per year: One
  • Program duration: 1 year
  • Accrediting body: Accreditation Council for Graduate Medical Education (ACGME)

Eligibility Requirements

Prior successful completion of an ACGME accredited AP/CP, AP, or CP Pathology residency training program.  Applicants who have completed 3 years of a 4-year AP/CP program will be considered on a case by case basis.

Additional links pertaining to eligibility requirements:

Additional links pertaining to MGP certification through the ABP

Selective Service System Registration:

  • All male applicants (as determined by gender assigned at birth for purposes of this requirement) who are US citizens or immigrants must have registered with the Selective Service System within 30 days of their 18th birthday, or arrival date into the USA. Individuals are eligible to register until the age of 26. Failure to register is a violation of federal law, and can face significant penalties, including loss of eligibility for citizenship for immigrants. Individuals who have not registered are not eligible for a variety of benefits including federal student aid, federal job training, and any job in the Executive Branch of the government (e.g. VA, Medicare, federal prisons), and are not allowed to work in federal facilities even as a resident or fellow.
  • Most Duke GME programs require rotations at federal facilities such as VA hospitals or prisons. All trainees in those programs must be eligible to work at those facilities. All applicants should ensure that they have registered for the Selective Service System if appropriate. If they have not registered, they should discuss this with their potential program director. Additional details can be found at https://www.sss.gov.

Important Dates*

  • 2024-2025 Fellowship: Filled
  • 2025-2026 Fellowship: Filled
  • 2026-2027 Fellowship: Open
    • Early Decision applications open: January 1, 2024
    • Early Decision application deadline: May 31, 2024
    • Regular Decision applications open: June 1, 2024
    • Earliest interview date: July 31, 2024
    • Earliest offer date: October 2, 2024

 

*The Duke MGP program participates in the MGP Unified Timeline published by the Association of Molecular Pathology (AMP), with dates reflected above. 

**Any trainee who is at Duke the year prior to the fellowship start date is eligible for early decision consideration (e.g. current Duke residents or trainees who will be completing a Duke fellowship the prior year).

 

How to Apply

Submit the following requested documents:

  1. Cover Letter
  2. MGP Application 
  3. Personal statement
  4. Curriculum Vitae
  5. ECFMG certificate (if applicable)
  6. Copies of USMLE/COMLEX transcripts
  7. Three letters of recommendation (including one from residency program director)

Address letters of recommendation to:

Jadee Neff, MD, PhD
Director, Molecular Genetic Pathology fellowship program, Department of Pathology
Duke University Health System
40 Duke Medicine Circle
Durham, NC 27710

Email your package to Program Coordinator Brittany Harris.

Applications will be accepted starting June 1 two years prior to the anticipated start date and will continue until the position is filled.

All applications are considered without regard to race, religion, gender, or national origin.

Stipends

Commensurate with the year of postgraduate training.

Personnel

Program Director

Jadee Neff, MD, PhD
Hematopathology and Molecular Genetic Pathology

Other Faculty

Michael Datto, MD, PhD

Anand Lagoo, MD, PhD

William Jeck, MD, PhD

Sarah Rapisardo, PhD

Catherine Rehder, PhD

Stefanos Rentas, PhD

Kristen Deak, PhD

Wen Shuai, MD, MS

Program Coordinator

Brittany Harris
Program Coordinator
Department of Pathology
Box 3712 DUMC
Durham, NC 27710
919.681.1563
Email