Hematopathology

at Duke University Medical Center and Duke Cancer Institute

Hematopathology is a comprehensive clinical and diagnostic Division and provides diagnostic services and specialized testing for patients with all types of leukemia, myeloid neoplasm, lymphoma, myeloma and benign hematologic disorders. We specialize in the diagnosis of a range of hematological disorders, including acute and chronic leukemia, myelodysplastic syndromes, myeloproliferative disorders, anemias and cytopenia, benign bone marrow and lymph node disorders, B-cell lymphomas and T-cell lymphomas and cutaneous lymphomas.

The Hematopathology Division provides consultation, laboratory testing and diagnosis, and coordinates specialized laboratories for molecular diagnostics, flow cytometry, cytogenetic and FISH analysis and specialized bone marrow testing.
The Division accepts prepared slides, processed tissue and fresh specimens for diagnostic consultation and additional testing as appropriate. For information regarding submission of specimens for consultations or second opinion, please contact the Hematopathology secretary by calling 1-919-681-6674 (Fax to 919-684-1856).

Hematopathology Experts at Duke University Medical Center and Cancer Institute
Division faculty have strong expertise in the diagnosis of leukemia and lymphoma in adults and children. A comprehensive approach to diagnosis integrates standard histologic and cytologic findings with results from specialty laboratories at Duke, including Flow Cytometry, Molecular Diagnostics, Cytogenetics, Hematology, Immunopathology, and Image Analysis laboratories. Crucial prognostic information is available through these state-of-the-art tests, providing vital support for the selection of the correct treatment regimen. The Hematopathology Division is located in the Duke Medical Center, Duke South Hospital.
 

Faculty

Ken H. Young, MD PhD  Professor and Director of the Hematopathology Division. Dr. Young is an outstanding hematopathologist and an internationally known investigator in the field of blood cancer. He has extensive experience in the diagnosis of hematologic cancers, has lectured nationally and internationally on various hematology topics particularly lymphoma and myeloma pathology. He has published 226 original peer-reviewed articles and 52 review articles, many in high impact journals (Nature Clin Onc Review, JCO, Blood, Leukemia and Clinical Cancer Research). His contributions to the hematology field include the development of novel technologies, as well as molecular and genetic biomarkers for classification of blood cancer and lymphoid neoplasms. Dr. Young’s research is funded by the National Institute of Health/National Cancer Institute (NIH/NCI). Dr. Young has been listed in Best Doctors in the United States.

Anand S. Lagoo, MD, PhD  As a diagnostic hematopathologist, my clinical interests are primarily focused on hemato-lymphoid malignancies  (leukemia, lymphoma, Hodgkin disease, multiple myeloma, and others).  These diagnostic interpretations are based on careful synthesis of findings from morphological examination of blood, bone marrow and lymphoid tissue coupled with a plethora of ancillary studies including flow cytometry, immunohistochemistry, cytogenetics and molecular diagnostics. As medical director of the Clinical Flow Cytometry laboratory, I oversee the accuracy of these high complexity diagnostic tests and am engaged in the development and validation of new tests crucial in continued care of the patients with leukemia, lymphoma, and myeloma. My translational research interests include the study of pathological changes following non-conventional treatments for myeloid, lymphoid, and plasma cell neoplasms and evaluating the spectrum of lymphoid tissue involvement by plasmacytic / plasmacytoid cells.

Jadee Neff, MD, PhD.   The majority of my time is devoted to microscopically examining tissue and bone marrow biopsies to diagnose hematologic malignancies (leukemia, lymphoma, myeloma, etc.) and testing patients’ DNA (from tumors or from blood) to detect actionable somatic or inherited mutations.  I strive for excellence in my clinical work by providing accurate diagnoses as rapidly and cost-efficiently as possible.  My research interests involve  1) understanding the biology of chronic leukemias/lymphomas of cytotoxic lymphocytes and  2) exploring the immunomodulatory response to neoplastic disease and developing methods to monitor and thereby refine tumor immunotherapy.

Endi Wang, MD, PhD.   As a diagnostic pathologist, I focus the diagnostic activities on hematopoietic diseases, particularly hematolymphoid neoplasms (leukemia, lymphoma, etc.).  In addition, I conduct clinical-related research, which consists primarily of case studies and case series investigations. My primary scholarly interests include therapy, immune status or other intrinsic or environmental factors as causes for hematopoietic neoplasms, and genetic analysis of neoplastic evolution in leukemia/lymphoma.  Refer to the published works since 2004.

Contact Information

Dr. Ken H. Young
Director, Division of Hematopathology, Department of Pathology
40 Duke Medicine Circle
Rm M-345, Davison Building
DUMC 3712
Durham, NC 27710
Office phone: 1-919-668-7568; Fax: 1-919-684-1856 and Email

Ms. Donna Noblitt, Sr. Administrative Assistant
Division of Hematopathology
40 Duke Medicine Circle
DUMC 3712
Durham, NC 27710
Phone: 1-919-681-6674 and Email

Anand S. Lagoo, MD, PhD, Endi Wang, MD, PhD, Jadee Neff, MD, PhD, Ken Young MD PhD
Faculty
Ken H. Young MD PhD

Ken H. Young, MD PhD

Director, Hematopathology Division

DUMC 3712

Durham, NC 27710

Office: 919-668-7568

Email

Eric Carlsen, MD PhD

Eric Carlsen, MD PhD

DUMC 3712

Durham, NC 27710

Office: 919-684-2429

Fax: 919-684-1856

Email

Anand S. Lagoo, MD, PhD

Anand S. Lagoo, MD, PhD

DUMC 3712

Durham, NC 27710

Office: 919-668-0921

Fax: 919-684-1856

Email

Jadee Neff, MD PhD

Jadee Neff, MD PhD

DUMC 3712

Durham, NC 27710

Office: 919-681-9894

Email

Wen Shuai, MD

Wen Shuai, MD MS

DUMC 3712

Durham, NC 27710

Office: 919-681-0251

Email

Endi Wang, MD, PhD

Endi Wang, MD, PhD

DUMC 3712

Durham, NC 27710

Office: 919-684-2486

Fax: 919-684-1856

Email