Department Members Present at Tisch’s Brain Tumor Center’s Annual Retreat

By Jamie Botta

Duke Pathology was well- represented at Preston Robert Tisch's Brain Tumor Center's Annual Retreat, held June 8-9th. Giselle López, MD, PhD, (pictured) served as a co-chair along with Dr. Justin Lowe and Dr. Michael Brown.

Many faculty members presented along with López, including Yiping He, PhD, Roger McLendon, MD, and Christopher J. Pirozzi, PhD. Additionally, Alexandra Hoyt-Miggelbrink, a graduate student in Pathology, was selected to give a trainee flash talk about her thesis project studying a novel exhaustion marker that regulates TOX expression.

  • He gave a presentation titled “Endolysosomes in Glioblastoma Pathogenesis.”
  • McLendon’s talk was titled “The Brain Tumor Center Biorepository: State of the Lab, 2023”
  • Pirozzi’s talk was titled “Mutant IDH-Mediated Suppression of the Th17 Lineage in Glioma: Biologic Impact and Therapeutic Potential.” In it, he discussed his team’s finding that mutant IDH1 leads to a decrease in the Th17 population of cells, an underexplored immune cell in glioma. They’re investigating whether Th17 restoration has any therapeutic value.
Left to right: Yiping He, PhD, Roger McLendon, MD, Christopher Pirozzi, PhD
Left to right: Yiping He, PhD, Roger McLendon, MD, Christopher Pirozzi, PhD

Share