The Department of Defense awarded a Prostate Cancer Research Program’s Early Investigator Research Award to Xue Jiang, PhD, a postdoctoral fellow in Jiaoti Huang’s, MD, PhD, research laboratory.
Work from the Huang lab has demonstrated that catabolism of glutamine (a non-essential amino acid) carbon is critically needed by advanced prostate cancer cells. Although targeting this pathway inhibits prostate cancer cells, therapy resistance is inevitable. Jiang will study the role of glutamine nitrogen metabolism and explore a synergistic therapeutic strategy of inhibiting both glutamine carbon and nitrogen utilization pathways to treat advanced and therapy-resistant prostate cancer.
Congratulations Xue!