Pathology Grand Rounds - A Mouse Model Reveals How Granulomas Eradicate Bacterial Infection

During this activity, attendees will learn: * The innate immune response is critical to clear normally harmless environmental pathogens * A form of regulated cell death called pyroptosis prevents environmental pathogens from infecting macrophages * The innate immune system forms granulomas around a lesion caused by an intracellular pathogen that replicates in neutrophils * Understand the visual presentation of one example of a granuloma response