Pathology Grand Rounds - The “Blood”-erfly effect: Geopolitical Consequences of Hematologic Disease Amongst European Royals

At the conclusion of this activity, learners should be able to: * Review the role of anti-K in hemolytic disease of the fetus and newborn (HDFN) *Explain how the English Reformation was a direct consequence of recurrent HDFN in the Tudor family * Review pathophysiology and clinical manifestations of Hemophilia B-aka "The Royal Disease" *Explain how Hemophilia B led to the rise of communism