Yuan Receives DoD Early Investigator Research Award

Fuwen Yuan, PhD

Fuwen Yuan PhD, a postdoctoral associate in the laboratory of Dr. Qianben Wang, has been selected as a recipient of the 2019 Department of Defense (DoD) Prostate Cancer Research Program Early Investigator Award. 

This two-year research award is dedicated to supporting young scientists in the early stages of their careers, and allows them to develop a research project and further their intellectual development as prostate cancer researchers of the future. Dr. Yuan’s funded proposal is entitled “Targeting castration-resistant prostate cancer by engineering the 3’ untranslated region”. In this project, Fuwen will determine the biological function and clinical relevance of cancer-promoting genes transcribed with shortened 3’ untranslated regions (3’ UTR) in lethal castration-resistant prostate cancer (CRPC). He will also determine the biological impact and therapeutic potential of reversing these 3’ UTR length changes by CRISPR-based technologies.

The success of this research may offer new avenues for the treatment of CRPC and enhance the well-being of prostate cancer patients. Dr. Yuan received his Bachelor’s degrees in Medicine and Psychology (double major) in 2015, and his Ph.D. in Biochemistry and Molecular Biology in 2018 from Peking University in China. He joined the Wang lab in 2018, focusing on the molecular mechanisms of anti-androgen-induced oncogenic transcription in prostate cancer as well as targeting CRPC by engineering 3’UTR.