Huang Lab Members

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Xufeng Chen, PhD

Dr. Xufeng Chen is a Research Scientist in the Pathology Department at Duke University. He received his Ph.D. degree in Oncology from Zhejiang University, Hangzhou, China in 1999, and then worked as a post-doc at City of Hope National Medical Center and University of Maryland. His researches focus on the molecular mechanisms in prostate cancer, including the mechanisms of carcinogenesis, the roles of androgen receptor signaling and neuroendocrine differentiation and the mechanism of tumor recurrence after hormonal therapy, and the development of novel therapies.

William Butler

Bill Butler

Bill Butler is currently a PhD student in the Pathology program at Duke University. He received his BS in Biochemistry from the University of Scranton in 2015 and his MS in Chemistry from the University of New Hampshire in 2018. His research interests include tumor biology, biomarker discovery, and therapeutic strategies, particularly in relation to hormone-dependent malignancies. He is currently studying the molecular pathways and epigenetic mechanisms leading to metastatic castration-resistant prostate cancer under the supervision of Dr. Jiaoti Huang.

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Ju Guo, PhD MD

Dr. Guo is currently a visiting scholar of Pathology at Duke University Medical Center. He received his Ph.D. degree in Urology from Huazhong University of Science and Technology, Wuhan, China. He is an associate professor of The First Affiliated Hospital of Nanchang University. His researches focus on the AR signaling pathway and prostate cancer.

 

Hailiang Hu, PhD

Dr. Hu is currently an Assistant Professor of Pathology at Duke University Medical Center. He was an Assistant Adjunct Professor of Pathology & Laboratory Medicine at David Geffen UCLA School of Medicine and a Member of Stem Cell and Cancer Program at UCLA Jonsson Comprehensive Cancer Center. Dr. Hu received his Bachelor degree of Chemistry from Nankai University and Ph.D. degree of Biochemistry and Molecular Biology from Shanghai Institute of Biochemistry, Chinese Academy of Sciences in 2000. Dr. Hu did his postdoctoral research training at UCLA School of Medicine from 2001 to 2007. Dr. Hu’s research interest includes: 1) develop combination therapy for castration-resistant prostate cancer and small cell neuroendocrine carcinoma and investigate the underlying molecular mechanisms; 2) study the role of DNA damage response in tumorigenesis and therapy resistance; 3) investigate the function of microRNAs in tumor progression and metastasis with focus on DNA damage-related microRNAs.

Weipeng Liu, PhD

Weipeng Liu, PhD 

Dr. Liu is currently a visiting scholar of Pathology at Duke University Medical Center. He received his Ph.D. degree in Urology from Sun Yat-sen University, Guangzhou, China. He is an associate professor of The First Affiliated Hospital of Nanchang University. His researches focus on the non-coding RNA and prostate cancer.

Feng Shi, MD

Dr. Shi is a visiting scholar of Pathology at Duke University Medical Center. Shi is an associate Senior Physician, from department of Pathology, Beijing Shijitan Hospital, Capital Medical University. She received her MD from Tianjin Medical University. She has studied for PhD degree in Beijing Chaoyang Hospital. Dr. Shi’s clinical interests includes: genitourinary pathology, gynecologic pathology, digestive pathology and lymphoma pathology. She is researching the molecular mechanism of prostate carcinogenesis and disease progression.  She also studies the novel strategies of drug combination to treat lethal prostate cancer.

Nan Song

Nan Song, MD PhD

Dr. Song is currently a visiting scholar of Pathology at Duke University Medical Center. He is from department of Urology, Beijing Shijitan Hospital, Capital Medical University. He received his Bachelor degree from Shanghai Tongji University in 2008, master degree from University of South China in 2012 and PhD degree from PLA general hospital in Beijing 2015. Dr. Song’s clinical interests includes: urologic tumor, genitourinary pathology. He is performing the research on the molecular pathways and metabolic mechanisms of prostate cancer under Dr. Jiaoti Huang’s direction at Duke.

 

Yi Sun

Yi Sun

Dr. Sun is currently a visiting scholar of Pathology at Duke University Medical Center. He is a PhD student of Urology Department of the West China Hospital of Sichuan University. He received his Bachelor degree from Binzhou Medical University in 2014 and Master degree from Sichuan University in 2017. During his scholarship period, he will focus on prostate cancer research under Dr. Jiaoti Huang’s direction at Duke

Chunhua Tu

Chunhua Tu, PhD

Chunhua Tu is currently a visiting scholar of Pathology at Duke University Medical Center. She received her Ph.D. degree in Obstetrics & Gynecology from Sun Yat-sen University, Guangzhou, China. She is an associate professor of the First Affiliated Hospital of Nanchang University. Her researches focus on the carcinogenesis of gynecologic cancer.

Huan Xu

Huan Xu, MD

Dr. Xu is currently a joint Ph.D. student of Pathology at Duke University Medical Center. He is a resident of Urology Department in Changhai Hospital of Second Military Medical University. He received his medical doctor degree in Qingdao University medical college in 2014 and received the master degree in Shanghai Jiao Tong University in 2017. Dr. Xu’s research will focus on the metabolism and prostate cancer research under Dr. Jiaoti Huang’s direction at Duke University.

Lingfan Xu, MD

Dr. Xu is currently a visiting scholar of Pathology at Duke University Medical Center. He is a resident of Urology Department of the First Affiliated Hospital of Anhui Medical University. He received his Bachelor degree and Master degree from Anhui Medical University in 2012 and 2015. And now he is a PhD student majoring in prostate disease from the same institution. During his scholarship period, he will focus on prostate cancer research under Dr. Jiaoti Huang’s direction at Duke.

Lab Alumni

 

Yan Chang, PhD

Dr. Chang is currently an visiting scholar of Pathology at Duke University Medical Center. She was an associate professor, from Institute of Clinical Pharmacology, Anhui Medical University. She received her Bachelor degree and Ph.D. degree from Institute of Clinical Pharmacology, Anhui Medical University in 2007 and 2012. Dr. Chang’s research interest includes: 1) develop new drug target and investigate the underlying molecular mechanisms in immune related disorders and cancer. 2) find biomarkers of early diagnosis and treatment.

Junyi Chen, MD PhD

Junyi Chen, MD PhD

Dr. Chen is a visiting scholar of Pathology at Duke University Medical Center. He is an associate professor, associate chief physician, the vice chairman of the department of Urology of the Second Affiliated Hospital of Fujian Medical University. He received his PH.D. degree from Second Military Medical University in 2011. He is studying neuroendocrine differentiation of prostate cancer and how amino acid metabolism is involved in disease progression and therapeutic resistance. He also has the opportunity to observe surgeries and urologic clinics focusing on genitourinary tumors.

Jaclyn Dong

Jaclyn Dong is a rising senior at Gretchen Whitney High School. She is currently being mentored by Dr. Chen. Her main project over the summer is a collaboration between Duke, Kaiser Permanente, and USC to determine whether measuring methylation changes will be effective for diagnosing prostate cancer in patients. The hypothesis is that differences in methylation levels indicate potential prostate cancer.

Justin Dong

Justin Dong is a student at Whitney High School visiting the Huang Lab at Duke as an intern. He worked as the key programmer on an AI project to diagnose retinal diseases at UCSD in 2017, published the research paper in Cell, and placed in the top 50 students of the US in the National Chemistry Olympiad. He is researching the differences in LDHA expression in LNCaP and PC3 cell lines and learning Western blot and qPCR techniques, as well as comparing the effects of LDHA inhibitor. He is also investigating the interactions between N-Myc and CXCR2, and will continue the AI project with prostate cancer images.

   

Er Jin, MD PhD

Dr. Jin is an associate Chief Physician in Department of Respiratory Medicine, Nanjing Medical University Affiliated Hangzhou Hospital. She is working on data imputing for the PROUD project at department of Pathology in Duke University.

Yanjing Li, PhD

Yanjing Li, PhD

Dr. Li is a post-doctoral associate in Dr. Huang’s lab. She received her Bachelor degree of Medicine from Peking University in 2013 and her Ph.D of Molecular Biology from UCLA in 2017. Dr. Li joined Duke Department of Pathology in Oct. 2017 to pursue her postdoctoral research training. Dr. Li’s research focuses are: 1) study the role of neuroendocrine cells in the development of therapy-resistant prostate cancer; 2) single-cell sequencing of human prostate cancer tissue to illustrate clonal evolution; 3) develop new therapeutic drug target against neuroendocrine cells for the treatment of lethal prostate cancer. Besides being a cancer research scientist, Dr. Li is also a skilled violinist and enjoys cooking in her spare time.

Yen-Nien Liu, PhD

Yen-Nien Liu, PhD

Yen-Nien Liu is a visiting research scholar in the Department of Pathology at the Duke University School of Medicine. Dr. Liu has completed his postdoctoral studies at National Cancer Institute, National Institutes of Health, USA. Dr. Liu is an associate professor of Taipei Medical University, Taiwan. Dr. Liu’s research interest includes 1) the signaling pathways on the regulation of genes involved in castration-resistant prostate cancer and neuroendocrine prostate cancer; 2) the regulatory mechanisms of the metabolic and inflammatory signalings that contribute to the drug resistance in prostate cancer.

Zoe Loh

Zoe Loh is currently a PhD student in the Pathology program at Duke University. She hopes to concentrate on prostate cancer metabolism during her time at Duke in the Huang laboratory. She graduated from the University of Notre Dame with a BS in Chemistry and as a member of the back to back national championship Division 1 fencing team. Zoe is originally from Toronto, Canada. Most recently Zoe worked as a researcher in the Fraser Lab where she spearheaded the SOFA- HDV ribozyme project, which proposes to prevent virus replication in vivo. She also worked in the McDowell Lab where she looks to develop an insecticide to combat the vector mosquito Aedes aegypti. Zoe is also a 3 time recipient of the ACC All-Academic Honors. 

Hongbing Mei, MD PhD

Dr. Mei is a visiting scholar of Pathology at Duke University Medical Center. He is a Chief Physician, Professor , Deputy Director of Urology Department of Shenzhen Second People's Hospital (The First Affiliated Hospital of Shenzhen University). Dr Mei is awarded the Degree of Doctor of Medicine from Huazhong University of Science and Technology in 2001 and 2004. He will be working under Dr. Jiaoti Huang’s direct supervision to study prostate cancer and bladder cancer. He will focus on molecular mechanism of prostate carcinogenesis and disease progression.

Shaoxi Niu

I am a PHD student from PLA general hospital Beijing China.  My previous research work focused on the study of a tumor suppresser gene in clear cell renal cell carcinoma. My current project at Duke University is to study the role of SPOP in prostate cancer.

Aifen Wang

Dr. Wang is a current visiting scholar of pathology at Duke University and focusing on develop therapy of castration-resistant prostatic cancer under the supervision of Dr. Jiaoti Huang.

She is Chief, Vice Chair of Obstetrics & Gynecology, Zhangjiagang Traditional Medical Hospital, Nanjing Traditional Medical University, Jiangsu, China. She earned medical degree in clinical medicine from Nantong University and Master’s degree in Obstetrics & Gynecology from Suzhou University.

Wenzhe (Wendy) Wang

Wenzhe Wang is a visiting research scholar in the department of pathology. She received her Ph.D. degree in Genetics from Zhejiang University, Zhejiang, China in 2009 and then worked as an associate professor at Zhejiang Academy of Medical Sciences

Yu Yin, PhD

Yu Yin, PhD, is a Visiting Scholar in the Department of Pathology at the Duke University School of Medicine. Dr. Yin is an associate professor of the Department of Pathology at the Anhui Medical University in China. Dr. Yin received her Master degree of Pathology from Anhui Medical University and PhD in Pathology from Nanjing Medical University. She was a Visiting Scholar in the Department of Pathology at UCLA from November 2015 to February 2016. Dr. Yin is a molecular pathology researcher and surgical pathologist. Currently she pursues prostate cancer research under Dr. Jiaoti Huang’s guidance at Duke.

Qingfu Zhang, MD

Dr. Zhang is currently an visiting scholar of Pathology at Duke University Medical Center. He is an associate professor of department of pathology, the first affiliated hospital of China Medical University. He received his Bachelor and Master degree from China Medical University in 2004 and 2008. Dr. Zhang’s research interest is the development of novel therapeutics for castration resistant prostate cancer (CRPC).